Sclerotium rolfsii is a soil borne pathogen, which commonly occurs in black pepper nurseries causing root rot. Biocontrol agents viz., Trichoderma harzianum and Streptomycetes spp. were tested against the pathogen under in planta challenge inoculated conditions. The results indicated that IISRBPAct 1 (Streptomyces sp.) was very effective in reducing the number of roots infected by Sclerotium rolfsii. The isolate was found to enhance the growth of plants as evidenced from the plant growth parameters